Release of Nuclear DNA Template Restrictions by Specific Polyribonucleotides

Science  15 Jan 1971:
Vol. 171, Issue 3967, pp. 176-178
DOI: 10.1126/science.171.3967.176


Certain synthetic homo- and copolyribonucleotide polymers are capable of releasing the DNA template restriction of isolated nuclei of rat liver cells when assayed with an excess of or in the absence of exogenous DNA polymerase. The purine homopolyribonucleotides are far more effective than are the pyrimidine polymers.