Functional Sequences Modulated by Morphological Transitions in Human Lymphoid Cells Grown in vitro

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Science  15 Jan 1971:
Vol. 171, Issue 3967, pp. 185-186
DOI: 10.1126/science.171.3967.185


Immunoglobulin-producing cells undergo a series of morphological transitions; each configuration displays specific functional attributes. The life cycle of immunocytes may be visualized as a series of functional compartments expressed by morphological sequences.