Reports

Retrograde Amnesia: Electroconvulsive Shock Effects after Termination of Rapid Eye Movement Sleep Deprivation

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Science  02 Apr 1971:
Vol. 172, Issue 3978, pp. 80-82
DOI: 10.1126/science.172.3978.80

Abstract

Mice that were deprived of rapid eye movement sleep for 2 days immediately after one-trial training in an inhibitory avoidance task and were given an electroconvulsive shock after deprivation displayed retrograde amnesia on a retention test given 24 hours later. Electroconvulsive shock produced no amnesia in comparable groups of animals that were not deprived of rapid eye movement sleep.