Electroencephalographic and Behavioral Alterations Produced by Δ1-Tetrahydrocannabinol

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Science  28 May 1971:
Vol. 172, Issue 3986, pp. 968-970
DOI: 10.1126/science.172.3986.968


The administration of small doses of Δl-tetrahydrocannabinol to cats with indwelling electrodes produced a disruption of both the electroencephalogram and behavior. Some of these alterations, including the appearance of a high-voltage slow wave electroencephalogram in the awake and moving animal, have been observed in cats that had been administered other drugs known to cause hallucinogenic states in man.