Sugar Transport: Effect of Temperature on Concentrative Uptake of α-Methylglucoside by Kidney Cortex Slices

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Science  04 Jun 1971:
Vol. 172, Issue 3987, pp. 1033-1034
DOI: 10.1126/science.172.3987.1033


The ability of renal cortical slices to accumulate a monosaccharide is enhanced at temperatures below 37°C. Increase in concentration gradients occurs despite a decrease in total sugar flux. The apparent explanation for this paradox is a proportionally greater inhibition of efflux.