Monosodium Glutamate: Absence of Hypothalamic Lesions after Ingestion by Newborn Primates

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Science  25 Jun 1971:
Vol. 172, Issue 3990, pp. 1342-1344
DOI: 10.1126/science.172.3990.1342


After receiving monosodium glutamate by stomach tube, the brains of infant macaques were perfused for examination by light and electron microscopy. No morphological differences were observed in the hypothalamic regions of treated and control monkeys. However, inadequately fixed tissue had the same appearance as that of the previously reported brain lesion in a newborn monkey.