Angiotensin-Forming Enzyme in Brain Tissue

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Science  02 Jul 1971:
Vol. 173, Issue 3991, pp. 64-65
DOI: 10.1126/science.173.3991.64


A renin-like enzyme is present in brain tissue and is independent of kidney and plasma renin. In the presence of homologous substrate it forms angiotensin. Administration of aldosterone significantly decreases this angiotensinforming enzyme activity, while administration of progesterone markedly enhances it.