Melatonin and Abnormal Movements Induced by L-Dopa in Mice

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Science  30 Jul 1971:
Vol. 173, Issue 3995, pp. 450-452
DOI: 10.1126/science.173.3995.450


Melatonin has blocked adventitious movements induced by L-dopa in intact mice. It has reversed the adventitious turning to the right, and it has induced running to the left in mice receiving L-dopa after a lesion in the right caudate nucleus.