Electroshock Effects on Brain Protein Synthesis: Relation to Brain Seizures and Retrograde Amnesia

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Science  30 Jul 1971:
Vol. 173, Issue 3995, pp. 454-456
DOI: 10.1126/science.173.3995.454


The effects of electroshock on brain seizure activity and brain protein synthesis were studied in male mice. A significant but short-lasting inhibition of brain protein synthesis and an increase in the amount of free leucine were produced by electroshock at intensities above the brain seizure threshold. Electroshock at intensities below the brain seizure threshold did not affect brain protein synthesis.