Transplanted Precursors of Nerve Cells: Their Fate in the Cerebellums of Young Rats

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Science  13 Aug 1971:
Vol. 173, Issue 3997, pp. 637-638
DOI: 10.1126/science.173.3997.637


The multiplying cells of the external granular layer in 7-day-old rats were labeled with [3H]thymidine. Slabs of the cerebellum were transplanted into the same region of uninjected hosts of the same age. The transplanted, undifferentiated cells of the donors migrated actively in the cerebellar cortex of the hosts and apparently differentiated there into basket and granule cells.