Anomalous Retinal Pathways in the Siamese Cat: An Inadequate Substrate for Normal Binocular Vision

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Science  15 Oct 1971:
Vol. 174, Issue 4006, pp. 302-305
DOI: 10.1126/science.174.4006.302


All major retinal pathways in the Siamese cat are abnormal, with almost total crossing of the projections to the pretectum and superior colliculus. These projections represent a marked disruption in the customary neural substrate for binocular vision, which implies a consequent impairment in stereoscopic depth perception. Crossed eyes, commonly seen in the Siamese cat, may therefore arise from a neuroanatomical defect in the primary visual pathways.