Herpesvirus Type 2 Isolated from Cervical Tumor Cells Grown in Tissue Culture

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Science  12 Nov 1971:
Vol. 174, Issue 4010, pp. 704-707
DOI: 10.1126/science.174.4010.704


A herpesvirus has been isolated from spontaneously degenerating cultures of cervical tumor cells grown in vitro. The virus was identified as a type 2 herpesvirus on the basis of biologic properties, including plaque morphology and microtubule formation in infected HEp-2 cells, and of immunologic specificity as determined by neutralization. Herpesvirus antigens and virus particles were not seen in duplicate cultures of viable cervical tumor cells.