Cell-Mediated Tumor Allograft Immunity: In vitro Transfer with RNA

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Science  14 Jan 1972:
Vol. 175, Issue 4018, pp. 204-205
DOI: 10.1126/science.175.4018.204


Specific inhibition of migration of spleen cells from C57B1/6J mice, which had rejected A/J sarcoma-1 tumors, occurred in the presence of A/J lymph mode antigens. The migration inhibitory effect was transferable to normal C57B1/6J spleen cells by RNA extracted from lymph nodes and spleens of immunized animals.