Ethanol Produces Muscle Damage in Human Volunteers

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Science  21 Jan 1972:
Vol. 175, Issue 4019, pp. 327-328
DOI: 10.1126/science.175.4019.327


Repeated administration of ethanol (42 percent of total calories) for 28 days increased serum creatine phosphokinase activity and produced ultrastructural changes in skeletal muscle of human volunteers. The data suggest that alcoholic myopathy results from ethanol toxicity, rather than from nutritional or other factors.