Lateral Interactions at Inner Plexiform Layer of Vertebrate Retina: Antagonistic Responses to Change

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Science  03 Mar 1972:
Vol. 175, Issue 4025, pp. 1008-1010
DOI: 10.1126/science.175.4025.1008


Lateral interactions at the inner plexiform layer of the retina of the mudpuppy were studied intracellularly after they were isolated from interactions at the outer plexiform layer with a special stimulus. The isolation was confirmed by recording no surround effect at bipolar cells under conditions that elicited a strong surround effect at ganglion cells. It appears that amacrine cell, which respond to spatiotemporal change at one retinal region, inhibit the response to change in on-off ganglion cells at adjacent sites.