Reports

Lack of Enhanced Oxygen Consumption by Polymorphonuclear Leukocytes on Phagocytosis of Virulent Salmonella typhi

Science  03 Mar 1972:
Vol. 175, Issue 4025, pp. 1010-1011
DOI: 10.1126/science.175.4025.1010

Abstract

Human polymorphonuclear leukocytes exhibit an enhanced rate of oxygen consumption during phagocytosis of relatively avirulent strains of Salmonella typhi or Staphylococcus aureus. However, phagocytosis of a virulent strain of Salmonella typhi is not associated with augmented oxygen consumption. The ability of a bacterial strain to alter the postphagocytic rate of oxygen consumption of polymorphonuclear leukocytes may be related to its in vivo virulence.

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