GABA Catabolism: Localization of Succinic Semialdehyde Dehydrogenase in Brain Motor and Sensory Nuclei

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Science  31 Mar 1972:
Vol. 175, Issue 4029, pp. 1479-1480
DOI: 10.1126/science.175.4029.1479


The localization of brain succinic semialdehyde dehydrogenase, a specific gamma-aminobutyric acid degradative enzyme, could potentially yield valuable information concerning the function of the enzyme. Application of a new histochemical technique for this enzyme has revealed characteristic patterns of neuronal staining that are contsistent within embryologically and functionally similar nuclei of the brainstem of the rat.