Genetic Polymorphism of Basic Proteins from Parotid Saliva

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Science  12 May 1972:
Vol. 176, Issue 4035, pp. 673-674
DOI: 10.1126/science.176.4035.673


In a study of 90 randomly chosen parotid salivas from Blacks three phenotypes were observed during acid-urea starch-gel electrophoresis. Inheritance was controlled by two codominant alleles at an autosomal locus. Of 101 Caucasians, one had a heterozygous phenotype indistinguishable electrophoretically from that in Blacks. Gene frequencies were: for Blacks, parotid basic protein (Pbl) = 0.84, (Pb2) = 0.16; for Caucasians, (Pbl) ~ 0.995, (Pb2) ~ 0.005.