Galactonic Acid in Galactosemia: Identification in the Urine

See allHide authors and affiliations

Science  12 May 1972:
Vol. 176, Issue 4035, pp. 683-684
DOI: 10.1126/science.176.4035.683


Galactose is converted to galactonic acid in vivo in man. Galactonate was isolated from the urine of galactosemia patients who had been given galactose orally. The identity of the galactonate was established by gas-liquid chromatography and by the preparation of derivatives.