Noradrenaline Nerve Terminals in Human Cerebral Cortices: First Histochemical Evidence

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Science  26 May 1972:
Vol. 176, Issue 4037, pp. 924-926
DOI: 10.1126/science.176.4037.924


The cerebral and cerebellar cortices of man are richly provided with varicose noradrenaline nerve terminals, which are visualized by fluorescence histochemistry of brain smears obtained by a new technique. The density of such nerves in human cortices equals that of the rat. The method permits simple and rapid analysis of noradrenergic nerves of the human cortex during routine neurosurgical operations.