Adaptation in Retinal Rods of Axolotl: Intracellular Recordings

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Science  16 Jun 1972:
Vol. 176, Issue 4040, pp. 1240-1242
DOI: 10.1126/science.176.4040.1240


Intracellular recordings of the late receptor potential from rods of isolated axolotl retinas revealed the existence of a dark adaptation mechanism that is independent of rod pigment regeneration. Response amplitude of individual rods was measured as a function of intensity both before and at various times after exposure to bleaching illumination. The rod sensitivity increased by at least 3 to 4 log units during a period of 15 to 25 minutes following the bleach. During this time rod pigment regeneration was either too small to be measured or was nonexistent in our preparation.