Axonal Transport of Tritium-Labeled Putrescine in the Embryonic Visual System of Zebrafish

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Science  23 Jun 1972:
Vol. 176, Issue 4041, pp. 1327-1329
DOI: 10.1126/science.176.4041.1327


The transport of [3H]putrescine is demonstrated by autoradiography in the retino-tectal tract of Brachydanio rerio embryos. Transport of [3H]putrescine appears to be more rapid than that of tritium-labeled protein and is not inhibited by a colchicine effect on axonal neurotubules as is protein transport. The radioactivity transported to the brain is found, on electrophoresis, in the putrescine fraction.