Tumor Etiology and Chromosome Pattern

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Science  23 Jun 1972:
Vol. 176, Issue 4041, pp. 1340-1341
DOI: 10.1126/science.176.4041.1340


Fibrosarcomas induced in Chinese hamsters and rats by Rous sarcomla virus and 7,12-dimethylbenz(a)anthracene are associated with nonrandom chromosome variation. Although histologically indistinguishable, the tumors induced by the virus or chemical in each host species are characterized by completely different karyotypic patterns.