Reports

Cytochalasin B: Inhibition of D-2-Deoxyglucose Transport into Leukocytes and Fibroblasts

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Science  30 Jun 1972:
Vol. 176, Issue 4042, pp. 1432-1434
DOI: 10.1126/science.176.4042.1432

Abstract

Cytochalasin B inhibits transport of D-2-deoxyglucose and of glucosamine into kukocytes, but does not impair uptake of kucine by these cells. This inhibitory action is rapid and reversible, and results in suppression of glycolysis. Cytochalasin B also blocks transport of D-2-deoxyglucose, but not of leucine, into mouse L strain fibroblasts.