Reports

Air Lead: Relation to Lead in Blood of Black School Children Deficient in Glucose-6-Phosphate Dehydrogenase

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Science  11 Aug 1972:
Vol. 177, Issue 4048, pp. 520-522
DOI: 10.1126/science.177.4048.520

Abstract

Forty-four black children at two elementary schools within 0.7 mile of a battery plant had significantly higher (P < .001) concentrations of lead in their bloods (34.1 ± 9.7, micrograms per 100 milliliters, mean ± standard deviation) than 122 students (26.3 ± 7.1) at seven schools 1 to 3 miles distant; 5 months later there was a comparable difference between red cell lead values (54.1 ± 18.5 versus 37.4 ± 12.6). Among the blacks, those deficient in glucose-6-phosphate dehydro-genase had a higher (P < .005) concentration of lead in the blood after correction for anemia (32.9 ± 9.7) than the nondeficient (25.7 ± 8.8), and a higher concentration in the red cells (47.3 ± 14.7 as compared to 35.6 ± 15.8, P < .001); the enzyme effect was independent of geographic location.

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