Intravenous Injection in Man of Δ9-Tetrahydrocannabinol and 11-OH-Δ9-Tetrahydrocannabinol

Science  18 Aug 1972:
Vol. 177, Issue 4049, pp. 633-635
DOI: 10.1126/science.177.4049.633


A microsuspension of Δ9-tetrahydrocannabinol and of its metabolic derivative 11-OH-Δ9-tetrahydrocannabinol has been prepared with 25 percent human serum albumin as the vehicle. Intravenous infusion of this preparation to humans indicates that both tetrahydrocannabinols are equally potent in producing the typical marihuana-like pschological and physiological effects.