Lysergic Acid Diethylamide and Stimulus Generalization: Rate-Dependent Effects

See allHide authors and affiliations

Science  25 Aug 1972:
Vol. 177, Issue 4050, pp. 720-722
DOI: 10.1126/science.177.4050.720


A stimulus generalization procedure was used to investigate the effects of LSD on sensitivity to auditory stimuli in rats. The shape of the generalization gradient was changed after administration of the drug only with a dose which produced decreases in relatively high rates of responding.