Relation between REM Sleep and Intracranial Self-Stimulation

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Science  22 Sep 1972:
Vol. 177, Issue 4054, pp. 1122-1124
DOI: 10.1126/science.177.4054.1122


Depriving rats of rapid eye movement (REM) sleep was shown to lower their thresholds and raise their response rates for rewarding brain stimulation. Conversely, allowing rats to self-stimulate while they were being deprived of this sleep form reduced the amount of REM rebound during recovery from deprivation. These results demonstrate a reciprocal relation between rewarding brain stimulation and REM sleep.