Coding Properties of Reticulocyte Lysine Transfer RNA's in Hemoglobin Synthesis

See allHide authors and affiliations

Science  29 Sep 1972:
Vol. 177, Issue 4055, pp. 1197-1199
DOI: 10.1126/science.177.4055.1197


Two isoacceptor transfer RNA's for lysine were found in rabbit reticulocytes. The codon recognition properties of these isoacceptors were studied in hemoglobin synthesis in a cell-free systemn. The two isoacceptors transferred lysine into different sites in hemoglobin, but showed no preference for one chain over the other. Codon cross recognition was less than 4 percent.