Location of the Second Gene Required for Expression of the Leukemia-Associated Mouse Antigen GIX

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Science  24 Nov 1972:
Vol. 178, Issue 4063, pp. 862-863
DOI: 10.1126/science.178.4063.862


Some mouse strains express GIX antigen on their thymocytes; others do not. Expression depends on two genes, Gv-1 and Gv-2, in linkage groups IX and I, respectively. Cells producing leukemia virus, however, express GIX antigen regardless of their inherited Gv-1 and Gv-2 genotype.