Chromosome Mapping in the Mouse

Science  01 Dec 1972:
Vol. 178, Issue 4064, pp. 949-955
DOI: 10.1126/science.178.4064.949


Chromosome banding techniques have permitted the identification of every normal chromosome in the mouse, Mus musculus, and the demonstration of strain differences. By identifying the chromosomes involved in a series of translocations, it has been possible to assign 14 of the 19 known linkage groups to 14 different chromosomes. These powerful cytological methods promise to revolutionize cytogenetic studies in higher organisms.