Centric Fusion and Trisomy for the LDH-B Locus in Brook Trout, Salvelinus fontinalis

Science  01 Dec 1972:
Vol. 178, Issue 4064, pp. 992-994
DOI: 10.1126/science.178.4064.992


Cytogenetic analyses showed that a trisomic male brook trout of genotype BB'B'' for one of the lactate dehydrogenase subunit loci had a karyotype with two extra arms appearing as a metacentric chromosome. The metacentric chromosome probably arose through centric fusion of two acrocentric or telocentric chromosomes—one of which carried the locus for subunit B—followed by nondisjunction.