Recognition of Cancer in vivo by Nuclear Magnetic Resonance

Science  22 Dec 1972:
Vol. 178, Issue 4067, pp. 1288-1290
DOI: 10.1126/science.178.4067.1288


Pulsed nuclear magnetic resonance has been used to differentiate in vivo between normal mouse tail tissue and a malignant transplanted melanoma, S91, located on the tail. The tumor displayed a nuclear (proton) spin-lattice relaxation time of ∼0.7 second contrasted with the simultaneously measured normal tail tissue relaxation time of ∼0.3 second.