Leukemia Virus Activation during Homograft Rejection

Science  04 May 1973:
Vol. 180, Issue 4085, pp. 500-502
DOI: 10.1126/science.180.4085.500


Activation of murine leukemia viruses, as detected by the mixed culture cytopathogenicity (XC) assay, followed the transplantation of A/J skin onto immunosuppressed BALB/c mice. Virus was found in most of the mice receiving both skin grafts and antilymphocyte serum, but not in animals receiving either the serum alone, skin graft alone, or no treatment.