Rejection of Tumor Cells in vitro

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Science  22 Jun 1973:
Vol. 180, Issue 4092, pp. 1289-1291
DOI: 10.1126/science.180.4092.1289


The emergence of lymphoblast-like cells, capable of rapidly destroying tumor cells, was observed in primary cultures of an antigenic sarcoma transplantable in strain 13 guinea pigs. It is likely that these cytotoxic cells represent the progeny of lymphocytes sensitive to tutmor antigens that had infiltrated the tumor tissue.