Reports

Serological Identification of an Ir-Region Product

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Science  13 Jul 1973:
Vol. 181, Issue 4095, pp. 167-169
DOI: 10.1126/science.181.4095.167

Abstract

Reciprocal immunization of congenic lines differing in the middle portion of the H-2 complex leads to the production of antibodies which react with an antigen or antigens controlled by the Ir region. The antigen designated Ir-1.1 seems to be present only on a subpopulation of lymphocytes from lymph nodes and spleen. It is absent on bone marrow cells.

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