Esterase, Malate, and Lactate Dehydrogenases Activity in Murine Neuroblastoma

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Science  03 Aug 1973:
Vol. 181, Issue 4098, pp. 450-451
DOI: 10.1126/science.181.4098.450


Mouse neuroblastoma tumors have only the fifth isozyme band (A4) of lactate dehydrogenase, whereas this band is missing in the brain which contained four other bands of lactate dehydrogenase. The α-esterase isozyme patterns of tumors, kidney, and brain are similar except that there is an additional slowest-moving form of esterase in all tumor tissues. The malate dehydrogenase pattern is not altered in any of the tissues.