Inherited Renal Cysts in Rats

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Science  03 Aug 1973:
Vol. 181, Issue 4098, pp. 451-452
DOI: 10.1126/science.181.4098.451


A strain of rats that form renal cysts has been developed. The number of visible cysts increases with age after animals are 20 days old. Micropuncture studies indicate that the cystic fluid has a variable sodium concentration, but that the ratios of inulin concentration in tubular fluid to that in plasma are high.