Reports

Exocytosis-Endocytosis Coupling in the Pancreatic Beta Cell

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Science  10 Aug 1973:
Vol. 181, Issue 4099, pp. 561-562
DOI: 10.1126/science.181.4099.561

Abstract

The stimulation of the release of insulin by glucose is accompanied by an enhanced uptake of cytochemically demonstrable horseradish peroxidase into endocytotic vesicles within the beta cells. An exocytosis-endocytosis coupling might represent a mechanism by which membrane constituents are recycled within the beta cells under conditions of increased secretory activity.