Intestinal Calcium Transport: Stimulation by Low Phosphorus Diets

Science  10 Aug 1973:
Vol. 181, Issue 4099, pp. 564-566
DOI: 10.1126/science.181.4099.564


Rats maintained on a low phosphorus diet supplemented with 25-hydroxyvitamin D3 show high intestinal calcium transport activity as compared to rats similarly treated but fed a diet containing adequate phosphorus. This increased transport activity is correlated with an increased biosynthesis of 1,25-dihydroxyvitamin D3, the probable metabolically active form of the vitamin in the intestine.