Isolation of a Neurotropic Type C Virus

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Science  07 Sep 1973:
Vol. 181, Issue 4103, pp. 945-947
DOI: 10.1126/science.181.4103.945


A neurogenic paralysis of the lower limb can be induced and serially transmitted in mice by a nontransforming type C virus strain that originated in an embryo of a wild mouse. The virus exerted a neurotropic effect on the anterior horn neurons.