Cell-Mediated Immune Responses in vitro: Interaction of Thymus-Derived Cells during Cytotoxic Allograft Responses in vitro

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Science  21 Sep 1973:
Vol. 181, Issue 4105, pp. 1170-1172
DOI: 10.1126/science.181.4105.1170


A mouse in vitro allograft system was used to check for synergism among thymus-derived cells during cell-mediated immune responses. Synergistic interactions occurred between thymus and thymus-derived lymphocytes. The majority of precursors of cytotoxic effector cells were peripheral thymus-derived cells; thymocytes acted mainly as amplifier cells.