Reports

Hypothalamic Obesity: The Myth of the Ventromedial Nucleus

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Science  02 Nov 1973:
Vol. 182, Issue 4111, pp. 488-490
DOI: 10.1126/science.182.4111.488

Abstract

Lesions restricted to the ventromedial nucleus of the hypothalamus were neither necessary nor sufficient for, and did not contribute to, the production of hypothalamic obesity. Hypothalamic lesions and knife cuts that do produce obesity damage the nearby ventral noradrenergic bundle or its terminals.