Aplysia Giant Cell: Soma-Axon Voltage Clamp Current Differences

See allHide authors and affiliations

Science  23 Nov 1973:
Vol. 182, Issue 4114, pp. 843-845
DOI: 10.1126/science.182.4114.843


Under voltage clamp, local membrane currents have been measured in several regions of the soma. The early inward current appears to pass largely through the membrane of the axon and of the soma near the axon in normal media. After 10-5 molar tetrodotoxin (TTX) is added to the bathing medium the larger inward current is found in the somatic membrane away from the axon. The late currents are larger at the soma in both normal and TTX media.