Probit Transformation: Improved Method for Defining Synchrony of Cell Cultures

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Science  07 Dec 1973:
Vol. 182, Issue 4116, pp. 1028-1030
DOI: 10.1126/science.182.4116.1028


Cell numbers can be converted to probits that are used to compare the degree and timing of synchronized cell cultures. Data from synchronous cultures of Chlorella pyrenoidosa have been analyzed by this method by means of a readily available computer program. The method can be used with any biological system that generates normal sigmoidal data.