Australia Antigen: Detection and Transmission in Shellfish

See allHide authors and affiliations

Science  11 Jan 1974:
Vol. 183, Issue 4120, pp. 80-81
DOI: 10.1126/science.183.4120.80


Australia antigen was found in clams contaminated by drainage of untreated sewage from a coastal hospital. In closed-system aquariums, the antigen was ingested by clams and transmitted to previously uninfected clams. In opensystem aquariums, the titer of Australia antigen decreased with time, suggesting viral concentration rather than replication.