Book Reviews

Diphenylhydantoin: Effects on Calcium Metabolism in the Chick

Science  15 Feb 1974:
Vol. 183, Issue 4125, pp. 671-673
DOI: 10.1126/science.183.4125.671


Rickets, hypocalcemia, decreased duodenal calcium transport, and reduction of calcium binding protein have been produced in chicks treated with diphenylhydantoin. These effects are directly related to diphenylhydantoin dose and inversely related to the intake of vitamin D3 (cholecalciferol).