B-Cell Alloantigens Determined by the H-2 Linked Ir Region Are Associated with Mixed Lymphocyte Culture Stimulation

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Science  22 Feb 1974:
Vol. 183, Issue 4126, pp. 757-759
DOI: 10.1126/science.183.4126.757


Cell surface antigens, controlled by genes located in the Ir region of the murine major histocompatibility complex, are shown serologically to be expressed preferentially on bone marrow-derived lymphocytes. These antigens may play a major role as stimulators in mixed lymphocyte cultures.