Electron Diffraction of Wet Biological Membranes

Science  05 Apr 1974:
Vol. 184, Issue 4132, pp. 77-78
DOI: 10.1126/science.184.4132.77


Electron diffraction patterns were obtained for the first time from single wet phospholipid bilayers and from wet human erythrocyte membranes by using a temperature-controlled electron microscope hydration stage. Selective area diffraction showed the existence of semicrystalline domains. A structural transition was observed at the transition temperature of the wet dipalmitoyl lecithin bilayer.