Reports

Erythrocyte Deformation in Human Muscular Dystrophy

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Science  12 Apr 1974:
Vol. 184, Issue 4133, pp. 165-166
DOI: 10.1126/science.184.4133.165

Abstract

Erythrocytes from patients with congenital muscular dystrophy exhibit dramatic surface deformation when observed with a scanning electron microscope. A similar alteration, but one affecting a smaller proportion of cells, occurs in the case of female carriers of the sex-linked Duchenne dystrophic condition. These observed changes in the erythrocyte surface may reflect a systemic defect in membrane properties.